Are cannabis and cannabinoids safe?

Cannabis and cannabinoids  have raised several concerns about the safety:

• The use of cannabis has been linked to an increased risk of motor vehicle crashes.
• Smoking cannabis during pregnancy has been linked to lower birth weight.
• Some people who use cannabis develop cannabis use disorder, which has symptoms such as craving, withdrawal, lack of control, and negative effects on personal and professional responsibilities.
• Adolescents using cannabis are four to seven times more likely than adults to develop cannabis use disorder.
• Cannabis use is associated with an increased risk of injury among older adults.
• The use of cannabis, especially frequent use, has been linked to a higher risk of developing schizophrenia or other psychoses (severe mental illnesses) in people who are predisposed to these illnesses.
• Marijuana may cause orthostatic hypotension (head rush or dizziness on standing up), possibly raising danger from fainting and falls.